|
週次 |
日期 |
單元主題 |
|
第1週 |
2/24 |
【課程說明及準備】:同學分組, 時程安排和確認, 上學期課程之回顧和討論 |
|
第2週 |
3/03 |
【張麗冠老師分享學術演講及研究心得】：請在下午4：25，於張麗冠老師實驗室（電顯館2樓）集合上課。此堂課不在系六教室。 |
|
第3週 |
3/10 |
【陳進庭老師分享】 |
|
第4週 |
3/17 |
<mark>【張麗冠老師團隊】</mark>
【林庭安】<br />A novel role for lipid droplets in the organismal antibacterial response. <br /><i><b> Elife, 1:e00003 (2012) </i></b> |
|
第5週 |
3/24 |
【荊士瑋】<br />Intravascular neutrophil extracellular traps capture bacteria from the bloodstream during sepsis. <br /><i><b>Cell Host Microbe. 12(3): p. 324-33. (2012)</b></i><br />【陳紀元】<br />Antimicrobial histones and DNA traps in invertebrate immunity: evidences in Crassostrea gigas. <br /> <b><i>J Biol Chem. 289(36): p. 24821-24831 (2014). </i></b> |
|
第6週 |
3/31 |
<mark>【楊啟伸老師團隊】</mark>
【張煜】<br />AAV-mediated photoreceptor transduction of the pig cone-enriched retina.<br /><b><i>Gene Ther. 18(7):637–645. (2011)</b></i>
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|
第7週 |
4/07 |
【蔡維庭】<br />In Vivo–Directed Evolution of a New Adeno-Associated Virus for Therapeutic Outer Retinal Gene Delivery from the Vitreous.<br /><b><i>Sci Transl Med 12 June 2013</b></i>. |
|
第8週 |
4/14 |
【陳政良】<br />Tyrosine capsid-mutant AAV vectors for gene delivery to the canine retina from a subretinal or intravitreal approach.<br /><b><i>Gene Therapy November 2013</b></i><br /> 【林蓓萱】<br />Targeting Channelrhodopsin-2 to ON-bipolar Cells With Vitreally Administered AAV Restores ON and OFF Visual Responses in Blind Mice.<br /><b><i>Molecular Therapy (2015)</b></i> |
|
第9週 |
4/21 |
期中考週 停課一次 |
|
第10週 |
4/28 |
<mark>【林晉玄老師團隊】</mark>
【李尹彤】<br />The microbial diversity of traditional spontaneously fermented lambic beer.<br /><b><i>PLoS One. 9(4):e95384 (2014)</b></i>. |
|
第11週 |
5/05 |
【林咸亨】<br />Microbiota and metabolites of aged bottled gueuze beers converge to the same composition.<br /><b><i>Food Microbiol. 47:1-11 (2015)</b></i>. |
|
第12週 |
5/12 |
【何新榮】<br />Large-scale selection and breeding to generate industrial yeasts with superior aroma production. <br /><b><i>Appl Environ Microbiol. 80(22):6965-6975 (2014)</b></i>. |
|
第13週 |
5/19 |
<mark>【陳進庭老師團隊】</mark>
【周加恩】<br />Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome<br /><b><i>Nature 423:293-298 (2003)</b></i>. |
|
第14週 |
5/26 |
＜延課至下週＞ |
|
第15週 |
6/02 |
【李依依】<br />Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson–Gilford progeria syndrome<br /><b><i>PNAS 109(41):16666-16671 (2012)</b></i>.<br />
【林月先】<br />Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts<br /><b><i>J Clin Invest. 121(7):2833–2844 (2011)</b></i>.
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|
第16週 |
6/09 |
<mark>【黃慶璨老師團隊】</mark>
【洪凱琳】<br /> Adoptive Cell Transfer Therapy Following Non-Myeloablative but Lymphodepleting Chemotherapy for the Treatment of Patients With Refractory Metastatic Melanoma. <br /><b><i>Journal of Clinical Oncology 10:2346-2357 (2005)</b></i>. |
|
第17週 |
6/16 |
【張景翔】<br /> High-Efficiency Transfection of Primary Human and Mouse T Lymphocytes Using RNA Electroporation. <br /><b><i>Molecular Therapy 13:151–159 (2006)</b></i>. <br /> 【蔡孟羲】<br /> Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia. <br /><b><i>The New England Journal of Medicine 365:725–733 (2011)</b></i>. |